
https://clinicaltrials.gov/ct2/show/NCT03981835?term=MARS&draw=2&rank
Sponsor: University of Texas Southwestern Medical Center, Dallas, Texas.
Grant support by: Chiesi Inc.
Principal Investigator: Jeffery Pelton, MD
The purpose of this registry is to evaluate DAPT management for patients that had PCI within the past 2 years and are undergoing surgery and the outcomes of their procedures. Data will be collected between 2 weeks prior and up to 37 days post-surgery.
https://clinicaltrials.gov/ct2/show/NCT03594175?term=READY+1&draw=2&rank=1
Sponsor: Chiesi Farmaceutici S.p.A
Principal Investigator: Gustavo Elias, MD
Sub Investigator: Sam Hijaz, MD
The purpose of this study is to demonstrate that CUSA-081 compared to placebo (normal saline) is better at restoring function to dysfunctional central venous access devices (CVADs) that have been blocked, compare CUSA-081 to alteplase (the current standard of care for occluded CVAD's), to study how often the CVADs gets blocked within 30 days and safety of the study drug.
Sponsor: The MT Group
Principal Investigator: Jeffery Pelton, MD
MT1410-A-Cancer Cohort: This study is designed to evaluate molecular characteristics in the blood samples of patients with Bladder, Brain, Colorectal, Esophageal, Gastric, Kidney, Liver, Ovarian, Pancreas, and Prostate Cancer. These samples will be used immediately or stored in a “Biobank”. Researchers will use these samples to try to develop new drugs or treatments or tests, as well as to study how individual differences may affect how drugs work.
MT9920 SOP: This study is designed to evaluate biomarkers in samples of patients with cancer. In many cases, the investigation is to identify novel markers to create new anti-cancer therapies and companion diagnostics. The biomarkers could be present in plasma, serum, or the tumor tissue itself. In addition, some tumors will be used in a culture environment to determine the efficacy of novel anti-cancer drugs and some tissues will be mined to isolate, purify, and culture tumor infiltrating lymphocytes, to evaluate immune reactivity in patients.
MT1822-A Lung Cancer: This study is designed to collect blood samples from patients that are diagnosed with lung cancer. Researchers will use the blood samples to try to develop new drugs, treatments or tests, and study how individual differences may affect how drugs work.
Principal Investigator: J. Timothy Sherwood, MD
Click here for more information on the Lung Cancer study.
MT 1822-B LDCT: This study is designed to evaluate biomarker/molecular characteristics in plasma and buffy coat collected from patients scheduled to undergo a low dose CT scan (LDCT) procedure.
Principal Investigator: J. Timothy Sherwood, MD
Click here for more information on the Low Dose CT scan study.
Sponsor: University of Nebraska Medical Center
Principal Investigator for Breast Registry: Darlene K. Blanchard, MD
Principal Investigator for Thoracic Registry: J. Timothy Sherwood, MD
Purpose of this registry: The data registry, Integrated Care Repository for Cancer Research (iCaRe2), will provide core support services for multi-disciplinary research for cancer. It is the hope that future research using information from this registry will lead to improved diagnosis, prevention, and treatment of cancer.
Click here for more information on the Breast Registry.
Click here for more information on the Thoracic Registry.
Prospective Registrational Trial to Define Real World Outcomes of Patients with Completely Resected Stage I or IIA Non-squamous Non-Small Cell Lung Cancer Identified as High, Intermediate, or Low Risk by a 14-Gene Prognostic Assay, DetermaRx, being Considered for Adjuvant Platinum-based therapy or other adjuvant therapy versus Observation.
Principle Investigator: J Timothy Sherwood, MD
Sponsor: ViiV Healthcare
Principal Investigator: Norman Bernstein, MD
The BEYOND study is a prospective, observational, multisite cohort study of adult participants initiating treatment with Cabenuva (cabotegravir long-acting plus rilpivirine long-acting) in the US. The purpose of the BEYOND study is to better understand reasons why participants and clinicians have chosen to initiate Cabenuva, participants' reasons for switching to Cabenuva, their experience and satisfaction with Cabenuva, their medical history, and their quality of life.
Principal Investigator: Jeffrey Pelton, MD
This study will develop a prospective digital database regarding information on all patients with Stage I-III cutaneous melanoma (henceforth referred to as “Melanoma Database”). The database will include clinical details, pathology details, and Gene Expression Profile (GEP) results. The information in the database would be collected prospectively and would be used in future retrospective studies in correlating GEP results, and other clinical and pathologic details, with patient overall survival, recurrence rates and recurrence-free survival. Retrospective review of the database could also be used to examine what types of treatments patients received and patient outcomes after those treatments, especially correlated to GEP results.
https://clinicaltrials.gov/ct2/show/NCT03815175?term=xience+28&cntry=US&draw=2&rank=1
Sponsor: Abbott
Principal Investigator: Harish Chandra, MD
Sub Investigator's Thomas Martyak, MD, Prithvi Rai, MD
https://www.clinicaltrials.gov/ct2/show/NCT03218787?term=xience+90&rank=1
Sponsor: Abbott
Principal Investigator: Harish Chandra, MD
Sub Investigator's: Thomas Martyak, MD, Zeshan Rana, MD
https://www.clinicaltrials.gov/ct2/show/record/NCT02235545?term=optisure&rank=1
Sponsor: Abbott
Principal Investigator: Ashok Talreja, MD
Sub Investigator: Henry Clemo, MD
Sponsor: OncoCyte Corporation
Principal Investigator: J. Timothy Sherwood, MD
http://www.breastmicroseed.com/
https://www.clinicaltrials.gov/ct2/show/NCT02701244?term=concure&rank=1
Sponsor: Breast Microseed, Inc.
Principal Investigator: John Chinault, MD
https://www.clinicaltrials.gov/ct2/show/NCT03448419?term=Emperial+trial&rank=1
https://www.clinicaltrials.gov/ct2/show/NCT03448406?term=Emperial+trial&rank=2
Sponsor: Boehringer Ingelheim Pharmaceuticals, Inc.,
Principal Investigator: Anita Banerjee, MD
Sub Investigator: Anh Vu, MD
https://clinicaltrials.gov/ct2/show/NCT01468701?term=GLORIA&recrs=e&draw=2&rank=3
Sponsor: Boehringer Ingelheim Pharmaceuticals, Inc.,
Principal Investigator: Robert Vranian, MD