Current Clinical Research Trials
Cancer Trials
Integrated Care Repository for Cancer Research (iCaRe2)
Sponsor: University of Nebraska Medical Center
Principal Investigator for Breast Registry: Darlene K. Blanchard, MD
Principal Investigator for Thoracic Registry: J. Timothy Sherwood, MD
Purpose of this registry: The data registry, Integrated Care Repository for Cancer Research (iCaRe2), will provide core support services for multi-disciplinary research for cancer. It is the hope that future research using information from this registry will lead to improved diagnosis, prevention, and treatment of cancer.
Click here for more information on the Breast Registry.
Click here for more information on the Thoracic Registry.
Infectious Disease Trials
Observational Cohort Study of Cabenuva Utilization, Outcomes and Patient Experience in the United States (Beyond)
Sponsor: ViiV Healthcare
Principal Investigator: Norman Bernstein, MD
The BEYOND study is a prospective, observational, multisite cohort study of adult participants initiating treatment with Cabenuva (cabotegravir long-acting plus rilpivirine long-acting) in the US. The purpose of the BEYOND study is to better understand reasons why participants and clinicians have chosen to initiate Cabenuva, participants' reasons for switching to Cabenuva, their experience and satisfaction with Cabenuva, their medical history, and their quality of life.
Physician Initiated Studies
Meldb_ Development of a Prospective Database for Surgically Resectable Melanoma Patients With Gene Expression Profile Testing.
Principal Investigator: Jeffrey Pelton, MD
This study will develop a prospective digital database regarding information on all patients with Stage I-III cutaneous melanoma (henceforth referred to as “Melanoma Database”). The database will include clinical details, pathology details, and Gene Expression Profile (GEP) results. The information in the database would be collected prospectively and would be used in future retrospective studies in correlating GEP results, and other clinical and pathologic details, with patient overall survival, recurrence rates and recurrence-free survival. Retrospective review of the database could also be used to examine what types of treatments patients received and patient outcomes after those treatments, especially correlated to GEP results.
Previous Clinical Trials
XIENCE 28 USA - ABT-CIP
https://clinicaltrials.gov/ct2/show/NCT03815175?term=xience+28&cntry=US&draw=2&rank=1
Sponsor: Abbott
Principal Investigator: Harish Chandra, MD
Sub Investigators Thomas Martyak, MD, Prithvi Rai, MD
Xience 90: A Safety Evaluation of 3-Month Dapt After Xience Implantation for High Bleeding Risk (Hbr) Patients.
https://www.clinicaltrials.gov/ct2/show/NCT03218787?term=xience+90&rank=1
Sponsor: Abbott
Principal Investigator: Harish Chandra, MD
Sub Investigators: Thomas Martyak, MD, Zeshan Rana, MD
OPTISURE: Optisure Lead Study
https://www.clinicaltrials.gov/ct2/show/record/NCT02235545?term=optisure&rank=1
Sponsor: Abbott
Principal Investigator: Ashok Talreja, MD
Sub Investigator: Henry Clemo, MD
Oncocyte Lung: A Study to Evaluate a Panel of Blood Biomarkers for use in Patients undergoing Evaluation for Lung Cancer, ONC-LN-04
Sponsor: OncoCyte Corporation
Principal Investigator: J. Timothy Sherwood, MD
BMS-001: A Multicenter Registry Study of Breast Microseed Treatment for Early-Stage Breast Cancer; Breast Microseed Registry
http://www.breastmicroseed.com/
https://www.clinicaltrials.gov/ct2/show/NCT02701244?term=concure&rank=1
Sponsor: Breast Microseed, Inc.
Principal Investigator: John Chinault, MD
Emperial Trial 1245-0167: A Phase III Randomised, Double-Blind Trial to Evaluate the Effect of 12 Weeks Treatment of Once Daily Empagliflozin 10 MG Compared With Placebo on Exercise Ability and Heart Failure Symptoms, in Patients With Chronic Heart Failure With Reduced Ejection Fraction (Hfref) (Emperial-Reduced)
https://www.clinicaltrials.gov/ct2/show/NCT03448419?term=Emperial+trial&rank=1
Emperial Trial 1245-0168: A Phase III Randomised, Double-Blind Trial to Evaluate the Effect of 12 Weeks Treatment of Once Daily Empagliflozin 10 MG Compared With Placebo on Exercise Ability and Heart Failure Symptoms, in Patients With Chronic Heart Failure With Reduced Ejection Fraction (Hfref) (Emperial-Reduced)
https://www.clinicaltrials.gov/ct2/show/NCT03448406?term=Emperial+trial&rank=2
Sponsor: Boehringer Ingelheim Pharmaceuticals, Inc.,
Principal Investigator: Anita Banerjee, MD
Sub Investigator: Anh Vu, MD
GLORIA - AF: Global Registry on Long-Term Oral Anti-Thrombotic TReatment In PAtients with Atrial Fibrillation (Phase II/III)
https://clinicaltrials.gov/ct2/show/NCT01468701?term=GLORIA&recrs=e&draw=2&rank=3
Sponsor: Boehringer Ingelheim Pharmaceuticals, Inc.,
Principal Investigator: Robert Vranian, MD
READY 1: A Phase 3, Randomized, Double-Blind, Active and Placebo-Controlled Study on the Use of CUSA-081 For Dysfunctional Central Venous Access Devices (CVAD’s)
https://clinicaltrials.gov/ct2/show/NCT03594175?term=READY+1&draw=2&rank=1
Sponsor: Chiesi Farmaceutici S.p.A
Principal Investigator: Gustavo Elias, MD
Sub Investigator: Sam Hijaz, MD
Mtg-022 Translational Medicine: Discovery and Evaluation of Biomarkers/Pharmacogenomics for the Diagnosis and Personalized Management of Patients. Under the Mtg-022 Master Protocol Are the Following Sop Studies: Mt1410-A, mt9920, mt1822-a and Mt1822-B.
Sponsor: The MT Group
Principal Investigator: Jeffery Pelton, MD, J. Timothy Sherwood, MD